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ALK-IN-12 danziolide A 5)19(26)21(13

SKU: 12171038310

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Description

5)19(26)21(13

CAS Number: 50-78-2

InChi: InChI=1S/C49H74N14O13/c1-26(2)18-33(42(51)70)59-40(67)25-55-44(72)35(20-29-10-7-6-8-11-29)61-43(71)28(5)57-47(75)36(21-30-13-15-31(64)16-14-30)63-48(76)34(19-27(3)4)62-46(74)32(12-9-17-54-49(52)53)58-39(66)24-56-45(73)37(22-41(68)69)60-38(65)23-50/h6-8

InChi: InChI=1S/C25H27FN6O4/c1-14(2)36-16-5-6-18(26)17(10-16)19-12-29-23(27)22(30-19)24(33)31-20-11-28-8-7-21(20)32-9-3-4-15(13-32)25(34)35/h5-8

Bunaphtide

ALK-IN-12 danziolide A 5)19(26)21(13ALK IN 12 is a potent and orally active ALK inhibitor with an IC50 of 0. 18 nM. ALK IN 12 also inhibits IGF1R and InsR (IC50=20. 3 and 90. 6 nM). Antitumor activities. Product information CAS Number: 1197958 53 4 Molecular Weight: 500. 96 Formula: C24H30ClN6O2P Chemical Name: 5 chloro N4 [2 (dimethylphosphoryl)phenyl] N2 [2 methoxy 4 (4 methylpiperazin 1 yl)phenyl]pyrimidine 2, 4 diamine Smiles:

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